The fire started around 12:58 a.m., Thursday, May 9, at 188 South Main Street, in Ellenville at 613 Automotive, said Ellenville Police Chief Philip Mattracion.
Following the fire, the production company said they had temporarily suspended production but expected to resume shooting soon.
The building and some 20 vintage cars and film equipment were totally destroyed, luckily, the car dealer had moved its vehicles off the lot to allow for filming, the police said.
In addition, three nearby families had to be relocated due to their proximity to the fire and the intense damage, Mattracion said.
Set for release in 2020, the series tells the story of a family through the parallel lives of identical twin brothers, both played by Ruffalo.
Besides Ruffalo and former Nyack resident Rosie O'Donnell, the series also stars Ulster County resident and Oscar-winning actress Melissa Leo, Kathryn Hahn, and Juliette Lewis.
Filming for the series has also taken place in the City of Poughkeepsie; in the Town of Poughkeepsie; and other locations in Ulster County.
The cause of the fire remains under investigation.
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